Migraines are more than just headaches—they can cause throbbing pain, nausea, and sensitivity to light and sound. In Aberdeen, a trial is investigating a medicine called atogepant to see if it can help children and teenagers who get migraines. Atogepant is already used for adults. It is important to know if it safe and helps younger people too.

Chronic Migraine Prevention study (ClinicalTrials.gov ID: NCT06810505)

This study is for teenagers aged 12 to 17 with chronic migraines (15 or more headache days per month, with at least 8 being migraine days). Participants take either atogepant or a placebo (a tablet with no medicine) for 12 weeks. No one knows which one they are getting, not even the doctors. This is called a double-blinded study. This helps make the results fair and accurate. The goal is to see if atogepant can reduce the number of migraine days each month.

This study is part of a global effort to find better migraine treatments for young people. If successful, it could lead to new options that make life easier for those living with this painful condition.

Maggie, our senior children’s research nurse, says: “Migraine is such a horrible condition for young people. It affects every part of their lives. It’s rewarding to offer a new treatment when others haven’t worked.”

Migraines - Migraine | NHS inform